Neale Lab Research

The research of Neale Lab focuses on the discovery and understanding of function of genes in forest trees, especially those controlling complex traits, through genetic mapping and genomic science technologies. In the very near future, nearly all the genes in pine will have been cloned and their DNA sequences determined. The cloned genes will serve as tools for functional analysis which will lead to undertstanding of complex patterns of coordinated expression of genes leading to phenotype. Initially, we have focused on traits of practical value such as wood quality, growth,and disease resistance but we expect to expand our studies to identifying genes determining patterns of adaptation and response to environmental stresses.

     
  • ADAPT

    Wood stiffness is the most important property of structural lumber. Wood characteristics are particularly important...
  • ACE-SAP

    The ACE-SAP project involves the study of biological and genetic diversity in some plant and animal populations as well as aquatic systems of Trentino....
  • ADEPT

    The goal of the Allele Discovery of Economic Pine Traits (ADEPT) project is to develop an infrastructure for identifying alleles at candidate gene loci that can be used...
  • ADEPT2

    Our long term goal is to genetically dissect complex traits and understand the relationship between naturally occurring genetic and phenotypic variation in forest trees...
  • Agenda2020

    Wood stiffness is the most important property of structural lumber. Wood characteristics are particularly important...
  • CCGP

    We have formed an international collaboration called the Conifer Comparative Genomics Project (CCGP). The immediate goals of this project are to...
  • CRSP

    Goal #1, Develop further the bioinformatic, genomic and database resources for a Pinaceae comparative genomics infrastructure...
  • CTGN

    Conifer Translational Genomics Network
  • Dendrome

    Dendrome is a collection of forest tree genome databases and other forest genetic information resources for the international forest genetics community.
  • DFGP

    In the Douglas-Fir Genome Project we propose to use a population genomic approach called association mapping to identify the specific genes that are...
  • LGFHN

    US forests are being challenged by many natural and anthropgenic stresses, including introduced pathogens and insects, climate change...
  • LPGP

    The Loblolly-Pine Genomics Project is a multi-institutional network of research collaborators with a common and well-defined set of genomics research goals...
  • PBGP

    The DOE's Breaking the Biological Barriers to Cellulosic Ethanol report identifies poplar as one of the key...
  • SSGP

    This project aims to begin to investigate the genetic basis of adaptation in coast redwood using genome-based tools...
  • WPGP/WHISP

    The goal of this study is single nucleotide polymorphism (SNP) discovery in the North American members of the white pines (Pinus section strobus)...

Upcoming Events


April 24-27, 2012
The Second International Symposium on Biology of Rare and Endemic Plants
Fethiye,Muğla-Turkey

October 9-12, 2012
Genetics of Fagaceae
Agora - University of Bordeaux, Bordeaux, France

July 22-26, 2013
Forest Genetics 2013
Hilton Hotel, Whistler, BC

     

Latest Publications


Jermstad K.D., Reem A.M., WheelerN.C., Neale D.B. (1994) Inheritance of restriction fragment length polymorphisms, random amplified polymorphic DNAs and isozymes in coastal Douglas-fir.
Eckert A.J., Wegrzyn J.L., Cumbie W.P., Goldfarb B., Huber D.A., Tolstikoc V., Fiehn O., Neale D.B. (2011) Association genetics of the loblolly pine (Pinus taeda, Pinaceae) metabolome. New Phytologist.
Li Z., Gopal V., Li X., Davis J.M., Casella G. (2010) Simultaneous SNP Identification in Association Studies with Missing Data. Bioinformatics.
Chancerel E., Lepoittevin C., Le Provost G., Lin Y., Jaramillo-Correa J.P., Eckert A.J., Wegrzyn J.L., Zelenika D., Boland A., Frigerio J., Chaumeil P., Garnier-Gere P., Boury C., Grivet D., Gonzalez-Martinez S.C., Rouze P., Van de Peer Y., Neale D.B., Cervera M.T., Kremer A., Plomion C. (2011) Development and implementation of a highly-multiplexed SNP array for genetic mapping in maritime pine and comparative mapping with loblolly pine. BMC Genomics. 12:368-. Full Text.
Maloney P.E., Vogler D.R., Eckert A.J., Jensen C.E., Neale D.B. (2011) Population biology of sugar pine (Pinus lambertiana Dougl.) with reference to historical disturbances in the Lake Tahoe Basin: Implications for restoration. Forest Ecology & Management. 262:770-779. Full Text.
Neale D.B., Kremer A. (2011) Forest tree genomics: growing resources and applications. Nature Reviews Genetics. 12:111-122. Full Text.
Jermstad K.D., Eckert A.J., Wegrzyn J.L., Delfino-Mix A., Davis D.A., Burton D.C., Neale D.B. (2011) Comparative mapping in Pinus: sugar pine (Pinus lambertiana Dougl.) and loblolly pine (Pinus taeda L.). Tree Genetics and Genomes. 7:457-468. Full Text.
Palle S.R., Seeve C.M., Eckert A.J., Cumbie W.P., Goldfarb B., Loopstra C.A. (2011) Natural variation in expression of genes involved in xylem development in loblolly pine (Pinus taeda L.). Tree Genetics and Genomes. 7:193-206. Full Text.
Cumbie W.P., Eckert A.J., Wegrzyn J.L., Whetten R., Neale D.B., Goldfarb B. (2011) Association genetics of carbon isotope discrimination, height, and foliar nitrogen in a natural population of Pinus taeda L.. Heredity. 107:105-114. Full Text. Supplemental.
Ersoz E.S., Wright M.H., Gonzalez-Martinez S.C., Langley C.H., Neale D.B. (2010) Evolution of Disease Response Genes in Loblolly Pine: Insights from Candidate Genes. PLoS ONE. 5:1-12. Full Text.

Latest Meeting Abstracts


Neale D.B. 2012. Genomics-Based Breeding in Forest Trees: Are We There Yet and Why We Need a Reference Genome to Finish the Job. USDA - NIFA and DOE - BER Project Director Meeting. January 13, 2012.
Zapata-Valenzuela J., Isik F., Maltecca C., Wegrzyn J.L., Neale D.B., Whetten R.W. 2011. Genomic Selection In A Cloned Population Of Loblolly Pine. Plant & Animal Genomes XIX Conference. January 15 - January 19, 2011. Information.
Chhatre V.E., Byram T.D., Neale D.B., Wegrzyn J.L., Krutovsky K.V. 2011. High-Density SNP Genotyping Of East Texas Loblolly Pine (Pinus taeda L.). Plant & Animal Genomes XIX Conference. January 15 - January 19, 2011. Information.
Wegrzyn J.L., Figueroa B., Yu J.J., Choi M., Eckert A.J., Neale D.B. 2011. Bioinformatic Solutions For Data Storage, Analysis, And Interpretation In Forest Genomics: Overview Of The Tools And Resources From The Dendrome Project. Plant & Animal Genomes XIX Conference. January 15 - January 19, 2011. Information.
Chhatre V.E., Byram T.D., Neale D.B., Wegrzyn J.L., Krutovsky K.V. 2011. Population Structure And Association Mapping Analysis Of Adaptive Traits In East Texas Loblolly Pine (Pinus taeda L.). Plant & Animal Genomes XIX Conference. January 15 - January 19, 2011. Information.